Inverse Regulation of Lipocalin-2/24p3 Receptor/SLC22A17 and Lipocalin-2 Expression by Tonicity, NFAT5/TonEBP and Arginine Vasopressin in Mouse Cortical Collecting Duct Cells mCCD(cl.1): Implications for Osmotolerance

The rodent collecting duct (CD) expresses a 24p3/NGAL/lipocalin-2 (LCN2) receptor (SLC22A17) apically, possibly to mediate high-affinity reabsorption of filtered proteins by endocytosis, although its functions remain uncertain. Recently, we showed that hyperosmolarity/-tonicity upregulates SLC22A17...

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Detalles Bibliográficos
Autores principales: Probst, Stephanie, Scharner, Bettina, McErlean, Ruairi, Lee, Wing-Kee, Thévenod, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862280/
https://www.ncbi.nlm.nih.gov/pubmed/31671521
http://dx.doi.org/10.3390/ijms20215398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862280/
https://www.ncbi.nlm.nih.gov/pubmed/31671521
http://dx.doi.org/10.3390/ijms20215398

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