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GLYX-13 pretreatment ameliorates long-term isoflurane exposure-induced cognitive impairment in mice
Accumulating evidence indicates that inhalation anesthetics induce or increase the risk of cognitive impairment. GLYX-13 (rapastinel) acts on the glycine site of N-methyl-D-aspartate receptors (NMDARs) and has been shown to enhance hippocampus-dependent learning and memory function. However, the mec...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862406/ https://www.ncbi.nlm.nih.gov/pubmed/31535661 http://dx.doi.org/10.4103/1673-5374.264466 |