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GLYX-13 pretreatment ameliorates long-term isoflurane exposure-induced cognitive impairment in mice

Accumulating evidence indicates that inhalation anesthetics induce or increase the risk of cognitive impairment. GLYX-13 (rapastinel) acts on the glycine site of N-methyl-D-aspartate receptors (NMDARs) and has been shown to enhance hippocampus-dependent learning and memory function. However, the mec...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Gong, Xiang-Dan, Zhao, Xin, Qian, Yue, Gu, Xiao-Ping, Xia, Tian-Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862406/
https://www.ncbi.nlm.nih.gov/pubmed/31535661
http://dx.doi.org/10.4103/1673-5374.264466