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20S proteasome and glyoxalase 1 activities decrease in erythrocytes derived from Alzheimer’s disease patients

As a result of accumulating methylglyoxal and advanced glycation end products in the brains of patients with Alzheimer’s disease, it is considered a protein precipitation disease. The ubiquitin proteasome system is one of the most important mechanisms for cells to degrade proteins, and thus is very...

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Detalles Bibliográficos
Autores principales: Lv, Hui, Wei, Gui-Yuan, Guo, Can-Shou, Deng, Yu-Feng, Jiang, Yong-Ming, Gao, Ce, Jian, Chong-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862418/
https://www.ncbi.nlm.nih.gov/pubmed/31535667
http://dx.doi.org/10.4103/1673-5374.264473