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Serotonin 5-HT(4) Receptor Agonists Improve Facilitation of Contextual Fear Extinction in an MPTP-Induced Mouse Model of Parkinson’s Disease

Previously, we found that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease (PD) model mice (PD mice) showed facilitation of hippocampal memory extinction via reduced cyclic adenosine monophosphate (cAMP)/cAMP-dependent response element-binding protein (CREB) signaling,...

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Detalles Bibliográficos
Autores principales: Ishii, Toshiaki, Kinoshita, Ken-ichi, Muroi, Yoshikage
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862438/
https://www.ncbi.nlm.nih.gov/pubmed/31717815
http://dx.doi.org/10.3390/ijms20215340