Combined 2D-QSAR, Principal Component Analysis and Sensitivity Analysis Studies on Fluoroquinolones’ Genotoxicity

In this paper, two-dimensional quantitative structure–activity relationship (2D-QSAR) and principal component analysis (PCA) methods were employed to screen the main parameters affecting the genotoxicity of fluoroquinolones (FQs), and the rules affecting the genetic toxicity of FQs were investigated...

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Detalles Bibliográficos
Autores principales: Du, Meijin, Zhang, Dan, Hou, Yilin, Zhao, Xiaohui, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862474/
https://www.ncbi.nlm.nih.gov/pubmed/31661905
http://dx.doi.org/10.3390/ijerph16214156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862474/
https://www.ncbi.nlm.nih.gov/pubmed/31661905
http://dx.doi.org/10.3390/ijerph16214156

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