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Unravelling the Regions of Mutant F508del-CFTR More Susceptible to the Action of Four Cystic Fibrosis Correctors

Cystic fibrosis (CF) is a genetic disease associated with the defective function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein that causes obstructive disease and chronic bacterial infections in airway epithelia. The most prevalent CF-causing mutation, the deletion of phe...

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Detalles Bibliográficos
Autores principales: Amico, Giulia, Brandas, Chiara, Moran, Oscar, Baroni, Debora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862496/
https://www.ncbi.nlm.nih.gov/pubmed/31683989
http://dx.doi.org/10.3390/ijms20215463