Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP(+)-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons

α-Synuclein is an abundant neuronal protein that accumulates in insoluble inclusions in Parkinson′s disease and other synucleinopathies. Fatty acids partially regulate α-Synuclein accumulation, and mesencephalic dopaminergic neurons highly express fatty acid-binding protein 3 (FABP3). We previously...

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Detalles Bibliográficos
Autores principales: Kawahata, Ichiro, Bousset, Luc, Melki, Ronald, Fukunaga, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862506/
https://www.ncbi.nlm.nih.gov/pubmed/31661838
http://dx.doi.org/10.3390/ijms20215358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862506/
https://www.ncbi.nlm.nih.gov/pubmed/31661838
http://dx.doi.org/10.3390/ijms20215358

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