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Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP(+)-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons

α-Synuclein is an abundant neuronal protein that accumulates in insoluble inclusions in Parkinson′s disease and other synucleinopathies. Fatty acids partially regulate α-Synuclein accumulation, and mesencephalic dopaminergic neurons highly express fatty acid-binding protein 3 (FABP3). We previously...

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Detalles Bibliográficos
Autores principales:	Kawahata, Ichiro, Bousset, Luc, Melki, Ronald, Fukunaga, Kohji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862506/ https://www.ncbi.nlm.nih.gov/pubmed/31661838 http://dx.doi.org/10.3390/ijms20215358

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