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What Does the History of Research on the Repair of DNA Double-Strand Breaks Tell Us?—A Comprehensive Review of Human Radiosensitivity

Our understanding of the molecular and cellular response to ionizing radiation (IR) has progressed considerably. This is notably the case for the repair and signaling of DNA double-strand breaks (DSB) that, if unrepaired, can result in cell lethality, or if misrepaired, can cause cancer. However, th...

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Detalles Bibliográficos
Autores principales: Berthel, Elise, Ferlazzo, Mélanie L., Devic, Clément, Bourguignon, Michel, Foray, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862552/
https://www.ncbi.nlm.nih.gov/pubmed/31717816
http://dx.doi.org/10.3390/ijms20215339