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Association of intron microsatellite status and exon mutational profiles of TP53 in human colorectal cancer

Microsatellite instability (MSI) and loss of heterozygosity (LOH), which cause genomic instability, contribute to cancer pathogenesis. However, only few studies have evaluated the association of a single microsatellite locus of the TP53 gene with the mutation spectra of TP53 exons. A total of 256 pa...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Feng, Dandan, Huo, Xueyun, Xiao, Xiaoqin, Chen, Zhenwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862561/
https://www.ncbi.nlm.nih.gov/pubmed/31777536
http://dx.doi.org/10.3892/etm.2019.8095