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Understanding G Protein Selectivity of Muscarinic Acetylcholine Receptors Using Computational Methods
The neurotransmitter molecule acetylcholine is capable of activating five muscarinic acetylcholine receptors, M1 through M5, which belong to the superfamily of G-protein-coupled receptors (GPCRs). These five receptors share high sequence and structure homology; however, the M1, M3, and M5 receptor s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862617/ https://www.ncbi.nlm.nih.gov/pubmed/31653051 http://dx.doi.org/10.3390/ijms20215290 |