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Gender Related Changes in Gene Expression Induced by Valproic Acid in A Mouse Model of Autism and the Correction by S-adenosyl Methionine. Does It Explain the Gender Differences in Autistic Like Behavior?

In previous studies we produced autism like behavioral changes in mice by Valproic acid (VPA) with significant differences between genders. S-adenosine methionine (SAM) prevented the autism like behavior in both genders. The expression of 770 genes of pathways involved in neurophysiology and neuropa...

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Detalles Bibliográficos
Autores principales: Weinstein-Fudim, Liza, Ergaz, Zivanit, Turgeman, Gadi, Yanai, Joseph, Szyf, Moshe, Ornoy, Asher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862653/
https://www.ncbi.nlm.nih.gov/pubmed/31652960
http://dx.doi.org/10.3390/ijms20215278