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Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring

An obesogenic diet adversely affects the endogenous mammalian circadian clock, altering daily activity and metabolism, and resulting in obesity. We investigated whether an obese pregnancy can alter the molecular clock in the offspring hypothalamus, resulting in changes to their activity and feeding...

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Detalles Bibliográficos
Autores principales: Cleal, Jane K., Bruce, Kimberley D., Shearer, Jasmin L., Thomas, Hugh, Plume, Jack, Gregory, Louise, Shepard, James N., Spiers-Fitzgerald, Kerry L., Mani, Ravi, Lewis, Rohan M., Lillycrop, Karen A., Hanson, Mark A., Byrne, Christopher D., Cagampang, Felino R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862679/
https://www.ncbi.nlm.nih.gov/pubmed/31671625
http://dx.doi.org/10.3390/ijms20215408