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Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring
An obesogenic diet adversely affects the endogenous mammalian circadian clock, altering daily activity and metabolism, and resulting in obesity. We investigated whether an obese pregnancy can alter the molecular clock in the offspring hypothalamus, resulting in changes to their activity and feeding...
Autores principales: | Cleal, Jane K., Bruce, Kimberley D., Shearer, Jasmin L., Thomas, Hugh, Plume, Jack, Gregory, Louise, Shepard, James N., Spiers-Fitzgerald, Kerry L., Mani, Ravi, Lewis, Rohan M., Lillycrop, Karen A., Hanson, Mark A., Byrne, Christopher D., Cagampang, Felino R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862679/ https://www.ncbi.nlm.nih.gov/pubmed/31671625 http://dx.doi.org/10.3390/ijms20215408 |
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