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Triptolide protects against TGF-β1-induced pulmonary fibrosis by regulating FAK/calpain signaling

The present study aimed to investigate the mechanism of anti-proliferative, anti-inflammatory and anti-fibrotic effects of triptolide (TPL) on activated lung fibroblasts by regulating the focal adhesion kinase (FAK) and calpain signaling pathways. The HFL-1 human foetal lung fibroblast cell line was...

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Detalles Bibliográficos
Autores principales: Zhang, Pingheng, Liu, Jian, Zong, Ruikai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862707/
https://www.ncbi.nlm.nih.gov/pubmed/31777561
http://dx.doi.org/10.3892/etm.2019.8127