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The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells

BACKGROUND: Testicular germ cell cancer (TGCC) develops from pre-malignant germ neoplasia in situ (GCNIS) cells. GCNIS originates from fetal gonocytes (POU5F1(+)/MAGE-A4(−)), which fail to differentiate to pre-spermatogonia (POU5F1(−)/MAGE-A4(+)) and undergo malignant transformation. Gankyrin is an...

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Detalles Bibliográficos
Autores principales:	Camacho-Moll, Maria E., Macdonald, Joni, Looijenga, L. H. J., Rimmer, Michael P., Donat, Roland, Marwick, John A., Shukla, C. J., Carragher, Neil, Jørgensen, Anne, Mitchell, Rod T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862764/ https://www.ncbi.nlm.nih.gov/pubmed/31744479 http://dx.doi.org/10.1186/s12885-019-6340-7

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