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Genetic dynamics in untreated CLL patients with either stable or progressive disease: a longitudinal study

Clonal evolution of chronic lymphocytic leukemia (CLL) often follows chemotherapy and is associated with adverse outcome, but also occurs in untreated patients, in which case its predictive role is debated. We investigated whether the selection and expansion of CLL clone(s) precede an aggressive dis...

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Detalles Bibliográficos
Autores principales: Ramassone, Alice, D’Argenio, Andrea, Veronese, Angelo, Basti, Alessio, Soliman, Shimaa Hassan AbdelAziz, Volinia, Stefano, Bassi, Cristian, Pagotto, Sara, Ferracin, Manuela, Lupini, Laura, Saccenti, Elena, Balatti, Veronica, Pepe, Felice, Rassenti, Laura Z., Innocenti, Idanna, Autore, Francesco, Marzetti, Laura, Mariani-Costantini, Renato, Kipps, Thomas J., Negrini, Massimo, Laurenti, Luca, Visone, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862808/
https://www.ncbi.nlm.nih.gov/pubmed/31744508
http://dx.doi.org/10.1186/s13045-019-0802-x