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Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data
BACKGROUND: Systematic interrogation of single-nucleotide variants (SNVs) is one of the most promising approaches to delineate the cellular heterogeneity and phylogenetic relationships at the single-cell level. While SNV detection from abundant single-cell RNA sequencing (scRNA-seq) data is applicab...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862814/ https://www.ncbi.nlm.nih.gov/pubmed/31744515 http://dx.doi.org/10.1186/s13059-019-1863-4 |