Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data

BACKGROUND: Systematic interrogation of single-nucleotide variants (SNVs) is one of the most promising approaches to delineate the cellular heterogeneity and phylogenetic relationships at the single-cell level. While SNV detection from abundant single-cell RNA sequencing (scRNA-seq) data is applicab...

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Detalles Bibliográficos
Autores principales: Liu, Fenglin, Zhang, Yuanyuan, Zhang, Lei, Li, Ziyi, Fang, Qiao, Gao, Ranran, Zhang, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862814/
https://www.ncbi.nlm.nih.gov/pubmed/31744515
http://dx.doi.org/10.1186/s13059-019-1863-4

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