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Certain Killer Immunoglobulin-Like Receptor (KIR)/KIR HLA Class I Ligand Genotypes Influence Natural Killer Antitumor Activity in Myelogenous Leukemia but Not in Acute Lymphoblastic Leukemia: A Case Control Leukemia Association Study

OBJECTIVE: Natural killers (NK) cell function is mainly controlled by the expression of killer immunoglobulin-like receptors (KIRs) and their ligation with the corresponding ligands. The objective of this study was to investigate the putative association of KIRs, HLA class I ligands, and KIR/ligand...

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Detalles Bibliográficos
Autores principales: Varbanova, Viktoria Plamenova, Mihailova, Snejina, Naumova, Elissaveta, Mihaylova, Anastasiya Petrova
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863033/
https://www.ncbi.nlm.nih.gov/pubmed/31337191
http://dx.doi.org/10.4274/tjh.galenos.2019.2019.0079