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MicroRNA-618 Directly Targets Metadherin mRNA To Suppress The Malignant Phenotype Of Osteosarcoma Cells By Reducing PTEN-AKT Pathway Output

PURPOSE: Dysregulation of microRNA-618 (miR-618) has been observed in multiple types of human cancer. However, whether miR-618 is implicated in osteosarcoma (OS) initiation and progression is still unclear. Hence, we measured the expression of miR-618 in OS tissues and cell lines. In addition, the r...

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Detalles Bibliográficos
Autores principales: Li, Bohan, Zhao, Jie, Zhao, Qian, Wu, Dongjin, Zhang, Cheng, Zhao, Kun, Song, Yang, Gao, Chunzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863364/
https://www.ncbi.nlm.nih.gov/pubmed/31814737
http://dx.doi.org/10.2147/OTT.S219440