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Characterization of Fully Recombinant Human 20S and 20S-PA200 Proteasome Complexes

Proteasomes are essential in all eukaryotic cells. However, their function and regulation remain considerably elusive, particularly those of less abundant variants. We demonstrate the human 20S proteasome recombinant assembly and confirmed the recombinant complex integrity biochemically and with a 2...

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Detalles Bibliográficos
Autores principales: Toste Rêgo, Ana, da Fonseca, Paula C.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863390/
https://www.ncbi.nlm.nih.gov/pubmed/31473102
http://dx.doi.org/10.1016/j.molcel.2019.07.014