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Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
The age-related failure to produce oligodendrocytes from oligodendrocyte progenitor cells (OPCs) is associated with irreversible neurodegeneration in multiple sclerosis (MS). Consequently, regenerative approaches have significant potential for treating chronic demyelinating diseases. Here, we show t...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863391/ https://www.ncbi.nlm.nih.gov/pubmed/31585093 http://dx.doi.org/10.1016/j.stem.2019.08.015 |