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Tandem domain swapping: determinants of multidomain protein misfolding
Tandem homologous domains in proteins are susceptible to misfolding through the formation of domain swaps, non-native conformations involving the exchange of equivalent structural elements between adjacent domains. Cutting-edge biophysical experiments have recently allowed the observation of tandem...
Autores principales: | Lafita, Aleix, Tian, Pengfei, Best, Robert B, Bateman, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863430/ https://www.ncbi.nlm.nih.gov/pubmed/31260947 http://dx.doi.org/10.1016/j.sbi.2019.05.012 |
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