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Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies

Natural flora is the richest source of novel therapeutic agents due to their immense chemical diversity and novel biological properties. In this regard, eighteen natural products belonging to different chemical classes were evaluated for their thymidine phosphorylase (TP) inhibitory activity. TP sha...

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Detalles Bibliográficos
Autores principales: Javaid, Sumaira, Shaikh, Muniza, Fatima, Narjis, Choudhary, M. Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863536/
https://www.ncbi.nlm.nih.gov/pubmed/31743355
http://dx.doi.org/10.1371/journal.pone.0225056