Role of α-Catenin and its mechanosensing properties in regulating Hippo/YAP-dependent tissue growth

α-catenin is a key protein of adherens junctions (AJs) with mechanosensory properties. It also acts as a tumor suppressor that limits tissue growth. Here we analyzed the function of Drosophila α-Catenin (α-Cat) in growth regulation of the wing epithelium. We found that different α-Cat levels led to...

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Detalles Bibliográficos
Autores principales: Sarpal, Ritu, Yan, Victoria, Kazakova, Lidia, Sheppard, Luka, Yu, Jessica C., Fernandez-Gonzalez, Rodrigo, Tepass, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863567/
https://www.ncbi.nlm.nih.gov/pubmed/31697683
http://dx.doi.org/10.1371/journal.pgen.1008454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863567/
https://www.ncbi.nlm.nih.gov/pubmed/31697683
http://dx.doi.org/10.1371/journal.pgen.1008454

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