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Role of α-Catenin and its mechanosensing properties in regulating Hippo/YAP-dependent tissue growth
α-catenin is a key protein of adherens junctions (AJs) with mechanosensory properties. It also acts as a tumor suppressor that limits tissue growth. Here we analyzed the function of Drosophila α-Catenin (α-Cat) in growth regulation of the wing epithelium. We found that different α-Cat levels led to...
Autores principales: | Sarpal, Ritu, Yan, Victoria, Kazakova, Lidia, Sheppard, Luka, Yu, Jessica C., Fernandez-Gonzalez, Rodrigo, Tepass, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863567/ https://www.ncbi.nlm.nih.gov/pubmed/31697683 http://dx.doi.org/10.1371/journal.pgen.1008454 |
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