A computational method for design of connected catalytic networks in proteins

Computational design of new active sites has generally proceeded by geometrically defining interactions between the reaction transition state(s) and surrounding side‐chain functional groups which maximize transition‐state stabilization, and then searching for sites in protein scaffolds where the spe...

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Detalles Bibliográficos
Autores principales: Weitzner, Brian D., Kipnis, Yakov, Daniel, A. Gerard, Hilvert, Donald, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863703/
https://www.ncbi.nlm.nih.gov/pubmed/31642127
http://dx.doi.org/10.1002/pro.3757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863703/
https://www.ncbi.nlm.nih.gov/pubmed/31642127
http://dx.doi.org/10.1002/pro.3757

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