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Efficacy of an anti-cancer strategy targeting SET in canine osteosarcoma

Osteosarcoma (OSA) is the most common bone tumor in dogs. Protein phosphatase 2A (PP2A), an evolutionary conserved serine/threonine protein phosphatase, is a crucial tumor suppressor. SET is a PP2A inhibitory protein that directly interacts with PP2A and suppresses its phosphatase activity. SET has...

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Detalles Bibliográficos
Autores principales: TSUJI, Shunya, OHAMA, Takashi, NAKAGAWA, Takayuki, SATO, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863715/
https://www.ncbi.nlm.nih.gov/pubmed/31527340
http://dx.doi.org/10.1292/jvms.19-0311