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Porcine IL-12 plasmid as an adjuvant improves the cellular and humoral immune responses of DNA vaccine targeting transmissible gastroenteritis virus spike gene in a mouse model

Transmissible gastroenteritis (TGE), caused by transmissible gastroenteritis virus (TGEV), is a highly infectious disease in pigs. Vaccination is an effective approach to prevent TGEV infection. Here, we evaluated the potential of TGEV S1 as a DNA vaccine and porcine interleukin (pIL)-12 as an adjuv...

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Detalles Bibliográficos
Autores principales: LI, Xunliang, LI, Pengchong, CAO, Liyan, BAI, Yunyun, CHEN, Huijie, LIU, He, REN, Xiaofeng, LI, Guangxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863717/
https://www.ncbi.nlm.nih.gov/pubmed/31474664
http://dx.doi.org/10.1292/jvms.18-0682