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EphA4 Negatively Regulates Myelination by Inhibiting Schwann Cell Differentiation in the Peripheral Nervous System

Myelin plays a crucial role in axon function recovery following nerve damage, and the interaction between Schwann cells (SCs) and regenerating axons profoundly affects myelin formation. Eph receptor A4 (EphA4), a member of the Eph tyrosine kinase receptor family, regulates cell-cell interactions via...

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Detalles Bibliográficos
Autores principales: Chen, Ruyue, Yang, Xiaoming, Zhang, Bin, Wang, Shengran, Bao, Shuangxi, Gu, Yun, Li, Shiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863774/
https://www.ncbi.nlm.nih.gov/pubmed/31798398
http://dx.doi.org/10.3389/fnins.2019.01191