DDR1 autophosphorylation is a result of aggregation into dense clusters

The collagen receptor DDR1 is a receptor tyrosine kinase that promotes progression of a wide range of human disorders. Little is known about how ligand binding triggers DDR1 kinase activity. We previously reported that collagen induces DDR1 activation through lateral dimer association and phosphoryl...

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Detalles Bibliográficos
Autores principales: Corcoran, David S., Juskaite, Victoria, Xu, Yuewei, Görlitz, Frederik, Alexandrov, Yuriy, Dunsby, Christopher, French, Paul M. W., Leitinger, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863838/
https://www.ncbi.nlm.nih.gov/pubmed/31745115
http://dx.doi.org/10.1038/s41598-019-53176-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863838/
https://www.ncbi.nlm.nih.gov/pubmed/31745115
http://dx.doi.org/10.1038/s41598-019-53176-4

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