A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants

The most common histological subtypes of cutaneous melanoma include superficial spreading and nodular melanoma. However, the spectrum of somatic mutations developed in those lesions and all potential druggable targets have not yet been fully elucidated. We present the results of a sequence capture N...

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Detalles Bibliográficos
Autores principales: Ticha, Ivana, Hojny, Jan, Michalkova, Romana, Kodet, Ondrej, Krkavcova, Eva, Hajkova, Nikola, Nemejcova, Kristyna, Bartu, Michaela, Jaksa, Radek, Dura, Miroslav, Kanwal, Madiha, Martinikova, Andra S., Macurek, Libor, Zemankova, Petra, Kleibl, Zdenek, Dundr, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863855/
https://www.ncbi.nlm.nih.gov/pubmed/31745173
http://dx.doi.org/10.1038/s41598-019-53636-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863855/
https://www.ncbi.nlm.nih.gov/pubmed/31745173
http://dx.doi.org/10.1038/s41598-019-53636-x

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