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Identification of lipid A deacylase as a novel, highly conserved and protective antigen against enterohemorrhagic Escherichia coli

Enterohemorrhagic E. coli (EHEC) is a major cause of large outbreaks worldwide associated with hemorrhagic colitis and hemolytic uremic syndrome. While vaccine development is warranted, a licensed vaccine, specific for human use, against EHEC is not yet available. In this study, the reverse vaccinol...

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Detalles Bibliográficos
Autores principales: Rojas-Lopez, Maricarmen, Martinelli, Manuele, Brandi, Valentina, Jubelin, Grégory, Polticelli, Fabio, Soriani, Marco, Pizza, Mariagrazia, Desvaux, Mickaël, Rosini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863877/
https://www.ncbi.nlm.nih.gov/pubmed/31745113
http://dx.doi.org/10.1038/s41598-019-53197-z