Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate

Many years ago, the natural secondary metabolite SF2312, produced by the actinomycete Micromonospora, was reported to display broad spectrum antibacterial properties against both Gram-positive and Gram-negative bacteria. Recent studies have revealed that SF2312, a natural phosphonic acid, functions...

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Detalles Bibliográficos
Autores principales: Krucinska, Jolanta, Lombardo, Michael N., Erlandsen, Heidi, Hazeen, Akram, Duay, Searle S., Pattis, Jason G., Robinson, Victoria L., May, Eric R., Wright, Dennis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863902/
https://www.ncbi.nlm.nih.gov/pubmed/31745118
http://dx.doi.org/10.1038/s41598-019-53301-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863902/
https://www.ncbi.nlm.nih.gov/pubmed/31745118
http://dx.doi.org/10.1038/s41598-019-53301-3

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