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An Integrated Analysis of Radial Spoke Head and Outer Dynein Arm Protein Defects and Ciliogenesis Abnormality in Nasal Polyps

Background: Nasal polyp (NP) is a chronic upper airway inflammatory disease that is frequently triggered by defective host-defense. However, the mechanisms underlying the impaired barrier function such as cilia-mediated mucociliary clearance remain poorly understood. Objective: To assess ciliary ult...

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Detalles Bibliográficos
Autores principales: Zi, Xiao-xue, Guan, Wei-jie, Peng, Yang, Tan, Kai Sen, Liu, Jing, He, Ting-ting, Ong, Yew-kwang, Thong, Mark, Shi, Li, Wang, De-yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863926/
https://www.ncbi.nlm.nih.gov/pubmed/31798623
http://dx.doi.org/10.3389/fgene.2019.01083