Alteration of the DNA Methylation Signature of Renal Erythropoietin-Producing Cells Governs the Sensitivity to Drugs Targeting the Hypoxia-Response Pathway in Kidney Disease Progression

Chronic kidney disease (CKD) affects more than 10% of the population worldwide and burdens citizens with heavy medical expenses in many countries. Because a vital erythroid growth factor, erythropoietin (EPO), is secreted from renal interstitial fibroblasts [renal EPO-producing (REP) cells], anemia...

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Detalles Bibliográficos
Autores principales: Sato, Koji, Kumagai, Naonori, Suzuki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863978/
https://www.ncbi.nlm.nih.gov/pubmed/31798631
http://dx.doi.org/10.3389/fgene.2019.01134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863978/
https://www.ncbi.nlm.nih.gov/pubmed/31798631
http://dx.doi.org/10.3389/fgene.2019.01134

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