miRNA Genetic Variants Alter Their Secondary Structure and Expression in Patients With RASopathies Syndromes

RASopathies are a group of rare genetic diseases caused by germline mutations in genes involved in the RAS–mitogen-activated protein kinase (RAS-MAPK) pathway. Whole-exome sequencing (WES) is a powerful approach for identifying new variants in coding and noncoding DNA sequences, including miRNAs. mi...

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Detalles Bibliográficos
Autores principales: de Carvalho, Joseane Biso, de Morais, Guilherme Loss, Vieira, Thays Cristine dos Santos, Rabelo, Natana Chaves, Llerena, Juan Clinton, Gonzalez, Sayonara Maria de Carvalho, de Vasconcelos, Ana Tereza Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863982/
https://www.ncbi.nlm.nih.gov/pubmed/31798637
http://dx.doi.org/10.3389/fgene.2019.01144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863982/
https://www.ncbi.nlm.nih.gov/pubmed/31798637
http://dx.doi.org/10.3389/fgene.2019.01144

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