Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase

Choline kinase alpha is a 457-residue protein that catalyzes the reaction between ATP and choline to yield ADP and phosphocholine. This metabolic action has been well studied because of choline kinase’s link to cancer malignancy and poor patient prognosis. As the myriad of x-ray crystal structures a...

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Detalles Bibliográficos
Autores principales: Kall, Stefanie L., Whitlatch, Kindra, Smithgall, Thomas E., Lavie, Arnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864063/
https://www.ncbi.nlm.nih.gov/pubmed/31745227
http://dx.doi.org/10.1038/s41598-019-53447-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864063/
https://www.ncbi.nlm.nih.gov/pubmed/31745227
http://dx.doi.org/10.1038/s41598-019-53447-0

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