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Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma
Glioblastoma (GBM) is the most common malignant primary tumor of the central nervous system. With no effective therapy, the prognosis for patients is terrible poor. It is highly heterogeneous and EGFR amplification is its most frequent molecular alteration. In this light, we aimed to examine the gen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864306/ https://www.ncbi.nlm.nih.gov/pubmed/31751860 http://dx.doi.org/10.1016/j.neo.2019.09.001 |