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Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma

Glioblastoma (GBM) is the most common malignant primary tumor of the central nervous system. With no effective therapy, the prognosis for patients is terrible poor. It is highly heterogeneous and EGFR amplification is its most frequent molecular alteration. In this light, we aimed to examine the gen...

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Detalles Bibliográficos
Autores principales: Muñoz-Hidalgo, Lisandra, San-Miguel, Teresa, Megías, Javier, Monleón, Daniel, Navarro, Lara, Roldán, Pedro, Cerdá-Nicolás, Miguel, López-Ginés, Concha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864306/
https://www.ncbi.nlm.nih.gov/pubmed/31751860
http://dx.doi.org/10.1016/j.neo.2019.09.001