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Transmembrane 163 (TMEM163) protein effluxes zinc

Recent investigations of rodent Tmem163 suggest that it binds to and transports zinc as a dimer, and that alanine mutagenesis of its two species-conserved aspartate (D123A/D127A) residues proposed to bind zinc, perturbs protein function. Direct corroboration, however, is lacking whether it is an inf...

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Detalles Bibliográficos
Autores principales: Sanchez, Vanessa B., Ali, Saima, Escobar, Adrian, Cuajungco, Math P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864316/
https://www.ncbi.nlm.nih.gov/pubmed/31697912
http://dx.doi.org/10.1016/j.abb.2019.108166