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Secretagogin Regulates Insulin Signaling by Direct Insulin Binding
Secretagogin (SCGN) is a β-cell enriched, secretory/cytosolic Ca(2+)-binding protein with unknown secretory regulation and functions. Recent findings suggest that SCGN deficiency correlates with compromised insulin response and diabetes. However, the (patho)physiological SCGN-insulin nexus remains u...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864339/ https://www.ncbi.nlm.nih.gov/pubmed/31734536 http://dx.doi.org/10.1016/j.isci.2019.10.066 |