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Secretagogin Regulates Insulin Signaling by Direct Insulin Binding

Secretagogin (SCGN) is a β-cell enriched, secretory/cytosolic Ca(2+)-binding protein with unknown secretory regulation and functions. Recent findings suggest that SCGN deficiency correlates with compromised insulin response and diabetes. However, the (patho)physiological SCGN-insulin nexus remains u...

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Detalles Bibliográficos
Autores principales:	Sharma, Anand Kumar, Khandelwal, Radhika, Kumar, M. Jerald Mahesh, Ram, N. Sai, Chidananda, Amrutha H., Raj, T. Avinash, Sharma, Yogendra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864339/ https://www.ncbi.nlm.nih.gov/pubmed/31734536 http://dx.doi.org/10.1016/j.isci.2019.10.066

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