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E6AP Promotes a Metastatic Phenotype in Prostate Cancer

Although primary prostate cancer is largely curable, progression to metastatic disease is associated with very poor prognosis. E6AP is an E3 ubiquitin ligase and a transcriptional co-factor involved in normal prostate development. E6AP drives prostate cancer when overexpressed. Our study exposed a r...

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Detalles Bibliográficos
Autores principales: Gamell, Cristina, Bandilovska, Ivona, Gulati, Twishi, Kogan, Arielle, Lim, Syer Choon, Kovacevic, Zaklina, Takano, Elena A., Timpone, Clelia, Agupitan, Arjelle D., Litchfield, Cassandra, Blandino, Giovanni, Horvath, Lisa G., Fox, Stephen B., Williams, Scott G., Russo, Andrea, Gallo, Enzo, Paul, Piotr J., Mitchell, Catherine, Sandhu, Shahneen, Keam, Simon P., Haupt, Sue, Richardson, Des R., Haupt, Ygal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864340/
https://www.ncbi.nlm.nih.gov/pubmed/31739170
http://dx.doi.org/10.1016/j.isci.2019.10.065