Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling

Stimulation of PC‐12 cells with epidermal (EGF) versus nerve (NGF) growth factors (GFs) biases the distribution between transient and sustained single‐cell ERK activity states, and between proliferation and differentiation fates within a cell population. We report that fibroblast GF (FGF2) evokes a...

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Detalles Bibliográficos
Autores principales: Blum, Yannick, Mikelson, Jan, Dobrzyński, Maciej, Ryu, Hyunryul, Jacques, Marc‐Antoine, Jeon, Noo Li, Khammash, Mustafa, Pertz, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864398/
https://www.ncbi.nlm.nih.gov/pubmed/31777174
http://dx.doi.org/10.15252/msb.20198947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864398/
https://www.ncbi.nlm.nih.gov/pubmed/31777174
http://dx.doi.org/10.15252/msb.20198947

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