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Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling
Stimulation of PC‐12 cells with epidermal (EGF) versus nerve (NGF) growth factors (GFs) biases the distribution between transient and sustained single‐cell ERK activity states, and between proliferation and differentiation fates within a cell population. We report that fibroblast GF (FGF2) evokes a...
Autores principales: | Blum, Yannick, Mikelson, Jan, Dobrzyński, Maciej, Ryu, Hyunryul, Jacques, Marc‐Antoine, Jeon, Noo Li, Khammash, Mustafa, Pertz, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864398/ https://www.ncbi.nlm.nih.gov/pubmed/31777174 http://dx.doi.org/10.15252/msb.20198947 |
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