Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes

Herein, we studied phorate for its toxicological effects in human lymphocytes. Phorate treatment for 3 h has induced significant increase in the lymphocytic DNA damage. Compared to control, comet data from highest concentration of phorate (1000 µM) showed 8.03-fold increase in the Olive tail moment...

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Detalles Bibliográficos
Autores principales: Saquib, Quaiser, Faisal, Mohammad, Ansari, Sabiha Mahmood, Wahab, Rizwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864401/
https://www.ncbi.nlm.nih.gov/pubmed/31762602
http://dx.doi.org/10.1016/j.sjbs.2019.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864401/
https://www.ncbi.nlm.nih.gov/pubmed/31762602
http://dx.doi.org/10.1016/j.sjbs.2019.04.008

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