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Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes
Herein, we studied phorate for its toxicological effects in human lymphocytes. Phorate treatment for 3 h has induced significant increase in the lymphocytic DNA damage. Compared to control, comet data from highest concentration of phorate (1000 µM) showed 8.03-fold increase in the Olive tail moment...
Autores principales: | Saquib, Quaiser, Faisal, Mohammad, Ansari, Sabiha Mahmood, Wahab, Rizwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864401/ https://www.ncbi.nlm.nih.gov/pubmed/31762602 http://dx.doi.org/10.1016/j.sjbs.2019.04.008 |
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