Species differences in ocular pharmacokinetics and pharmacological activities of regorafenib and pazopanib eye‐drops among rats, rabbits and monkeys

Age‐related macular degeneration (AMD) is the leading cause of severe vision impairment in patients over the age of 60 years. Choroidal neovascularization (CNV) is the hallmark of neovascular AMD and vascular endothelial growth factor (VEGF) plays a causal role in the formation of CNV. Although rego...

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Detalles Bibliográficos
Autores principales: Horita, Shinya, Watanabe, Miwa, Katagiri, Mai, Nakamura, Hiroaki, Haniuda, Hiroki, Nakazato, Tomoyuki, Kagawa, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864407/
https://www.ncbi.nlm.nih.gov/pubmed/31763044
http://dx.doi.org/10.1002/prp2.545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864407/
https://www.ncbi.nlm.nih.gov/pubmed/31763044
http://dx.doi.org/10.1002/prp2.545

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