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Anti-Cancer and Ototoxicity Characteristics of the Curcuminoids, CLEFMA and EF24, in Combination with Cisplatin

In this study, we investigated whether the curcuminoids, CLEFMA and EF24, improved cisplatin efficacy and reduced cisplatin ototoxicity. We used the lung cancer cell line, A549, to determine the effects of the curcuminoids and cisplatin on cell viability and several apoptotic signaling mechanisms. C...

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Detalles Bibliográficos
Autores principales: Monroe, Jerry D., Hodzic, Denis, Millay, Matthew H., Patty, Blaine G., Smith, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864451/
https://www.ncbi.nlm.nih.gov/pubmed/31671767
http://dx.doi.org/10.3390/molecules24213889